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INSM - Insmed - 2009 draadje

3.044 Posts
Pagina: «« 1 ... 10 11 12 13 14 ... 153 »» | Laatste | Omlaag ↓
  1. [verwijderd] 29 mei 2009 16:47
    quote:

    crackedtooth schreef:

    [quote=SPIKY]
    en we gaan weer lekker richting de $1,77
    [/quote]

    fijn bij verzwakkende dollar
    :p
    maakt me niks uit hou toch voorlopig het geld in de usa
  2. [verwijderd] 29 mei 2009 16:48
    spiky: dan nog... longterm grote kans op blijvend zwakkere dollar tov euro..

    dat je in US geinvesteerd blijft, wil niet zeggen dat je waarde in euros niet bij een sterkere dollar wilt locken
  3. [verwijderd] 29 mei 2009 18:44
    quote:

    SPIKY schreef:

    ik vind het stil hier ondanks toch weer een mooie stijging
    Ga toch echt nie binnen achter de pc zitten met dit weer.... en de sleeptop heeft een accu die het met moeite 15 minuten volhoudt....

    Prettig weekend !

    Riel
  4. [verwijderd] 30 mei 2009 08:39
    After Hours
    Last: $ 1.68 After Hours
    High: $ 1.80
    After Hours
    Volume: 6,200 After Hours
    Low: $ 1.63

    After Hours
    Time (ET) After Hours
    Price After Hours
    Share Volume
    18:05 $ 1.68 500
    16:51 $ 1.63 100
    16:08 $ 1.74 100
    16:08 $ 1.80 100
    16:08 $ 1.80 100
    16:08 $ 1.75 100
    16:08 $ 1.75 100
    16:08 $ 1.75 100
    16:04 $ 1.72 1,000
    16:04 $ 1.72 797
    16:02 $ 1.70 3,203

    eerst 1,75 zag ik ook en toen dit nog

  5. [verwijderd] 30 mei 2009 22:52
    quote:

    SPIKY schreef:

    After Hours
    Last: $ 1.68 After Hours
    High: $ 1.80
    After Hours
    Volume: 6,200 After Hours
    Low: $ 1.63

    After Hours
    Time (ET) After Hours
    Price After Hours
    Share Volume
    18:05 $ 1.68 500
    16:51 $ 1.63 100
    16:08 $ 1.74 100
    16:08 $ 1.80 100
    16:08 $ 1.80 100
    16:08 $ 1.75 100
    16:08 $ 1.75 100
    16:08 $ 1.75 100
    16:04 $ 1.72 1,000
    16:04 $ 1.72 797
    16:02 $ 1.70 3,203

    eerst 1,75 zag ik ook en toen dit nog

    Gezien het volume zegt dit niet zo veel. Maar hopen dat er de komende week een aanloop gaat komen.
  6. [verwijderd] 31 mei 2009 10:03
    Neoadjuvant, Multiple Dose, Dose Escalation Phase 1 Trial of the Clinical Safety and Molecular Efficacy of rhIGFBP-3 in Subjects with High Risk Prostate Cancer Who Have Elected to Undergo Radical Prostatectomy (IRB # 07-02-091) Study purpose:
    The optimal treatment for patients with locally advanced prostate cancer is particularly controversial. Both radiation therapy and radical prostatectomy have been used to treat advanced prostate cancer either alone or in combination. These approaches have significant limitations in their ability to eliminate locally advanced prostate cancer. Therefore, we desperately need new approaches to treating these patients that hold more promise for long-term local control. We propose to study the use of recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3) prior to radical prostatectomy, to improve the results of surgery for high-risk patients. This therapy is not yet approved by the US Food and Drug Administration (FDA).

    The purpose of this study is to evaluate the safety and effectiveness of rhIGFBP-3 prior to radical prostatectomy. Pre-study tumor biopsies used to establish diagnosis and post-study medication surgical specimens will be analyzed for different biomarkers. Biomarkers are substances in the body fluids or tissues whose levels can indicate if the study medication is having an effect in your body. This is a phase I study. The purpose of a phase I study is to find the best way to give an experimental product and how much of it can be given safely In this study, subjects will be assigned to groups that correspond with increasing doses of the study drug. Physicians watch subjects carefully for any harmful side effects.
    clinicaltrials.ucla.edu/body.cfm?xyzp...
  7. [verwijderd] 31 mei 2009 10:05
    Unraveling IGFBP-3 Actions in Human Disease

    The IGF system plays critical roles in somatic growth in an endocrine fashion (somatomedin hypothesis) as well as proliferation and differentiation of normal and malignant cells in a paracrine/autocrine fashion. IGFBP-3 is known to modulate the actions of IGFs in circulation as well as the immediate extracellular environment. Interestingly, apart from the ability to inhibit or enhance IGF actions, IGFBP-3 also exhibits very clear, distinct biologic effects independent of the IGF/IGF-I receptor axis. Over the past decade it has become widely appreciated that IGF/IGF-IR-independent actions of IGFBP-3 (antiproliferative and pro-apoptotic effects) contribute to improving the pathophysiology of a variety of human diseases such as cancer, diabetes and malnutrition. Recent studies have implicated interaction of IGFBP-3 with a variety of proteins or signaling cascades critical to cell cycle control and apoptosis, however, the actual mechanism of IGFBP-3 action is still unclear. This review reinforces the concept in support of the IGF/IGF-IR axis-independent actions of IGFBP-3 and delineates potential underlying mechanisms involved and subsequent biological significance, focusing in particular on functional binding partners and the clinical significance of IGFBP-3 in the assessment of cancer risk.

    sorry maar de Link wil niet.
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Aalberts 466 7.005
AB InBev 2 5.493
Abionyx Pharma 2 29
Ablynx 43 13.356
ABN AMRO 1.582 51.370
ABO-Group 1 22
Acacia Pharma 9 24.692
Accell Group 151 4.132
Accentis 2 264
Accsys Technologies 23 10.555
ACCSYS TECHNOLOGIES PLC 218 11.686
Ackermans & van Haaren 1 188
ADMA Biologics 1 34
Adomos 1 126
AdUX 2 457
Adyen 14 17.664
Aedifica 3 902
Aegon 3.258 322.680
AFC Ajax 538 7.087
Affimed NV 2 6.289
ageas 5.844 109.887
Agfa-Gevaert 14 2.048
Ahold 3.538 74.321
Air France - KLM 1.025 35.010
AIRBUS 1 11
Airspray 511 1.258
Akka Technologies 1 18
AkzoNobel 467 13.036
Alfen 16 24.412
Allfunds Group 4 1.469
Almunda Professionals (vh Novisource) 651 4.251
Alpha Pro Tech 1 17
Alphabet Inc. 1 405
Altice 106 51.198
Alumexx ((Voorheen Phelix (voorheen Inverko)) 8.486 114.819
AM 228 684
Amarin Corporation 1 133
Amerikaanse aandelen 3.836 242.832
AMG 971 133.167
AMS 3 73
Amsterdam Commodities 305 6.686
AMT Holding 199 7.047
Anavex Life Sciences Corp 2 486
Antonov 22.632 153.605
Aperam 92 14.961
Apollo Alternative Assets 1 17
Apple 5 381
Arcadis 252 8.736
Arcelor Mittal 2.033 320.625
Archos 1 1
Arcona Property Fund 1 286
arGEN-X 17 10.288
Aroundtown SA 1 219
Arrowhead Research 5 9.725
Ascencio 1 26
ASIT biotech 2 697
ASMI 4.108 39.087
ASML 1.766 106.261
ASR Nederland 21 4.452
ATAI Life Sciences 1 7
Atenor Group 1 484
Athlon Group 121 176
Atrium European Real Estate 2 199
Auplata 1 55
Avantium 32 13.642
Axsome Therapeutics 1 177
Azelis Group 1 64
Azerion 7 3.392