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Crucell Terug naar discussie overzicht

Draadje OT, bijzaken & geleuter in de marge! - Deel 2

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  1. Hans Igor 8 januari 2009 20:58
    quote:

    flosz schreef:

    Briefpapier....
    contact
    Pleon bv
    Amsterdamseweg 206
    1182 HL Amstelveen
    Postbus 75537
    NL-1070 Amsterdam
    T +31 (0)20 487 40 00
    F +31 (0)20 669 72 65
    marc.jansen (at) pleon.com

  2. [verwijderd] 8 januari 2009 21:04
    quote:

    flosz schreef:

    Te Koop, Crucell-archief en een 1958 Fender strat. (left-handed)………………..

    Die bronzen beeldjes nog even vasthouden Flosz, die zijn over 10 jaar goud geld waard.

    En daarbij.... het staat zo leuk op de schoorsteen :).

    Babs
  3. forum rang 10 voda 8 januari 2009 21:16
    Het is weer fantastisch Flosz! Hoeveel TB beslaat jouw database bestand eigenlijk (als ik dat vragen mag) ? :-)

    Groetjes,

    Hans
  4. flosz 8 januari 2009 21:17
    quote:

    babs11 schreef:

    [quote=flosz]

    Te Koop, Crucell-archief en een 1958 Fender strat. (left-handed)………………..

    [/quote]

    Die bronzen beeldjes nog even vasthouden Flosz, die zijn over 10 jaar goud geld waard.

    En daarbij.... het staat zo leuk op de schoorsteen :).

    Babs
    Misschien dat ik er van yellowf. ook wel achter mag gaan zitten...
  5. [verwijderd] 10 januari 2009 11:13
    Crucell strooit met miljoenen

    'Je moet ervan uit gaan dat een groot deel van de beursgenoteerde biotechbedrijven nooit aan winst toekomt.' Crucell-commissaris Nol Hoevenaars had bijna gelijk toen hij die woorden tegen Quote uitsprak. Toevallig boekte Crucell in het derde kwartaal van 2008 € 12 miljoen winst, voor het eerst sinds zijn oprichting in 1993. Maar dat is niet het belangrijkste, ook met een kwakkelend bedrijf kun je gierend binnenlopen, weten we sinds donderdag.

    Na het inmiddels zekere gerucht dat de Amerikaanse farmamoloch Wyeth een bod van rond $1 miljard wil doen op Crucell spoot de koers van het aandeel omhoog en noteert inmiddels €16.99, en dat is leuk voor de dappere aandeelhouder die in het bedrijf geloofde. En nog leuker voor Quote 500-lid Aat van Herk , nummer 31 met €666 miljoen. Want de man heeft met zijn Aat van Herk BV sinds december 2007 een belang van een fijne 11,01 % in het Leidse Biotechbedrijf. Dat pakket is sinds gisteren een slordige €78 miljoen waard. Peanuts voor Van Herk, toch leuk.

    Overigens maakte Crucell eerder al zijn oprichter Dinko Valerio miljonair. Bij de beursgang van het bedrijf in 1998 cashte Valerio al € 8 miljoen. Waarschijnlijk houdt de man (sinds 2004 geen bestuurder meer) nog steeds 502.500 opties aan met expiratiedatum 2011 aan. De waarde van dat pakket (uitoefenprijs €3,49) is no ongeveer €14,7 miljoen euro. Valerio zou daarmee nog meer verdienen als de huidige bestuursvoorzitter Ronald Brus die sinds gisteren aan opties en aandelen zo'n €8,4 miljoen waard is.

    Bron: www.quotenet.nl/biz/crucell_strooit_m...
  6. flosz 12 januari 2009 23:52
    Even Thijs uitzwaaien.
    Dank voor je inzet Thijs!
    ********************************

    Dit is misschien niet helemaal de juiste plaats, maar graag wil ik via jullie ook mededelen dat ik mijn werkzaamheden (als forummoderator) bij IEX per vandaag heb beëindigd.

    De laatste tijd zagen jullie me niet veel als forummoderator, maar ik heb toch een aantal jaren met plezier de discussies op de forums gevolgd. Ik zal, onder het alias thijs752, een aantal discussies blijven volgen, maar zal dus niet langer berichten verwijderen of vragen gericht aan IEX beantwoorden. De support wordt, zoals jullie wellicht weten, momenteel uitgevoerd door Jeroen, Alex, Paul, Ferdinand en Jasper. Voor contact kunnen jullie terecht op de bekende adressen (forum@iex.nl voor vragen over de IEX fora) .

    Bedankt voor de plezierige discussies de afgelopen jaren!

    Met vriendelijke groet,

    Thijs Vollenbroek
    www.iex.nl/forum/topic.asp?forum=23&t...
  7. flosz 15 januari 2009 08:16
    Nature Biotechnology 27, 3 - 5 (2009)
    doi:10.1038/nbt0109-3

    Biotech sector ponders potential 'bloodbath'
    Peter Mitchell1
    London
    A large proportion of small public biotech companies now find themselves at serious risk of going out of business, with not enough cash to see them through the next 12 months and negligible prospects of refinancing. As banks have run out of lending money, as hedge funds and private equity investors have shut up shop and the public equity markets spiraled into a free fall, financing options for cash-hungry biotech companies have dwindled. By the end of November, total capital raised by the industry had fallen by 56% from the previous year, according to data from BioCentury. By the end of this year, the global biotech landscape could look vastly different from the past.
    "The current crisis is unparalleled in its scope and severity," says Gautam Jaggi, senior manager at Ernst & Young Global Biotechnology, in New York, and it will lead to substantial consolidation, restructuring, layoffs and delistings (Box 1). According to the Biotechnology Industry Organization (BIO; Washington, DC), 180 quoted US biotech companies have less than a year's cash in hand—the level at which most CEOs, employees and investors find themselves swallowing hard and considering less palatable options for fueling a company. Of these, 120 have less than six months' breathing space (the majority are microcaps, Box 2 and Figs. 1 and 2).
    Volledig art. via: www.nature.com/nbt/journal/v27/n1/ful...

    Nature Biotechnology 27, 8 (2009)
    doi:10.1038/nbt0109-8a
    Myriad wins BRCA1 row
    Nayanah Siva
    Introduction
    After seven years of dispute, the European Patent Office (EPO) has decided to uphold Myriad Genetics' patent on the BRCA1 'breast cancer gene' but in a limited form. In 2001 patents were granted to Salt Lake City, Utah–based Myriad for using the genes BRCA1 and BRCA2 to diagnose women's predisposition to breast and ovarian cancers. But international research institutes and genetics societies filed an opposition to the patents. "It became clear that the patent owners did not intend to offer licenses [to other institutions], or at least not at a reasonable price," says Gert Matthijs from the Center for Human Genetics, University of Leuven, Belgium. "This [pricing issue] has angered the genetic community, even more than the idea that genes and diagnostic tests could be patented." As a result, EPO revoked the patent for BRCA1. Myriad then filed an appeal requesting that the patent be maintained in a revised form. The November 19 ruling gives the patent owners the right to collect royalties on tests carried out across Europe, although the patent's original scope has been reduced to cover only frameshift mutations, not BRAC1 itself. EPO says the patent cannot be contested at the European level; however, it is still possible for opponents to go to national courts to further reduce the scope of the patent. Myriad's William Hockett says the company is pleased with EPO's decision.
    www.nature.com/nbt/journal/v27/n1/ful...

    Nature Biotechnology 27, 10 (2009)
    doi:10.1038/nbt0109-10c
    Pfizer's $100 million stem cell stake
    Nayanah Siva
    Introduction
    Pfizer has launched Pfizer Regenerative Medicine, an independent research unit focused exclusively on using stem cells to develop new medicines. The New York–based company will spend more than $100 million over the next 3–5 years on the new initiative, which will employ 70 researchers based at two facilities, in Cambridge, Massachusetts, and Cambridge, UK. The UK group will focus on neural and sensory disorders, whereas the US team will concentrate on endocrine and cardiac research. In-house researchers will work with both embryonic and adult stem cells, but significant collaborations are also planned. Chief Scientific Officer Ruth McKernan, who will head the UK site, says: "We are keen to take advantage of successful work done by other companies and academic labs. We will be working with several collaborators and these will be announced in the new year." In the past, big pharma has shied away from investing in stem cell research, but Pfizer's move confirms that attitudes are changing. London's GlaxoSmithKline recently signed a $25 million four-year deal with Harvard University, and the venture funds of Basel-based Novartis and Roche helped bankroll Cellerix, a Madrid company testing stem cells from fat to treat rare skin conditions. Stanford University, California, also recently announced the construction of the world's largest stem cell research building to house over 600 scientists by 2010.
    www.nature.com/nbt/journal/v27/n1/ful...
  8. flosz 15 januari 2009 14:41
    January 15, 2009, 7:30 am
    Novartis’s Jimenez: Cafepharma Habitue
    Posted by Jeanne Whalen

    Attention, Novartis sales reps: Be careful about what you write next time you visit Cafepharma.com. Joe Jimenez may be watching.
    Jimenez, the big boss of Novartis’ pharmaceutical business, made a surprising admission to the Health Blog when we met with him recently in Switzerland. He’s an avid reader of Cafepharma, that virtual den of iniquity, where sales reps vie anonymously to top one another with gossip about their companies.
    We admit to visiting the site and its message boards now and again. If you haven’t been there, be warned the content can be sophomoric and downright raunchy at times.
    But there are insights to be had. A recent thread on the Novartis board kicks off a conversation about the relevance of sales reps, asking, “Is there anyone left who does not know that it is over?” The answer from the anonymous poster begins, “The pharmaceutical sales representative job as it exists today is done.”
    Jimenez checks in with Cafepharma to see what reps are saying about Novartis. “I read it because I like to get information from a lot of different places,” says Jimenez, who has been making big changes since taking over the pharma division in late 2007.
    He was particularly interested in the Cafepharma reaction to the U.S. sales force restructuring he announced in October, which resulted in about 1,500 job cuts. Overall, he says he found the anonymous feedback to be pretty positive.
    Last summer Jimenez even started a blog of his own, available only to Novartis employees, where he writes weekly posts and gets feedback. In his first message, Jimenez, captain of the Stanford swim team in his college days, wrote about how he found inspiration in Michael Phelps’s accomplishments at the Olympics.
    As for Cafepharma, Jimenez says he isn’t there looking for evil-doing to punish. “I take absolutely seriously anybody who internally reports something to me that is a violation of our code of conduct. But I wouldn’t take an anonymous thing on a Cafepharma post, because a lot of people have, you know, other agendas,” he said.
    We had to ask Jimenez if he’s ever tempted to write a message on Cafepharma? “No,” he answered.
    blogs.wsj.com/health/2009/01/15/novar...

    Wyeth board: www.cafepharma.com/boards/forumdispla...
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Accentis 2 267
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AIRBUS 1 12
Airspray 511 1.258
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Alfen 16 25.021
Allfunds Group 4 1.510
Almunda Professionals (vh Novisource) 651 4.251
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Alphabet Inc. 1 406
Altice 106 51.198
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Archos 1 1
Arcona Property Fund 1 286
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Aroundtown SA 1 220
Arrowhead Research 5 9.747
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ASIT biotech 2 697
ASMI 4.108 39.445
ASML 1.766 108.747
ASR Nederland 21 4.502
ATAI Life Sciences 1 7
Atenor Group 1 521
Athlon Group 121 176
Atrium European Real Estate 2 199
Auplata 1 55
Avantium 32 13.690
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Azerion 7 3.412